Depo Medrol vs Prednisone

This is a discussion thread · 37 replies
1 2 3 4 5
Mary:
I need to make a choice about whether to continue Cheeks (4-year-old shelter rescue, female, spayed, and with beautiful intact little feets! ) on Depo shots or do prednisone pills for her asthma and linear granuloma (rodent ulcer) problem.
One shot every two to three months keeps both under control. My vet tells me that is not a lot of Depo, so that she is not at a high risk for side effects. However, there are side effects with Depo including increased diabetes rates in cats so inclined and impaired liver and kidney function.
He told me today that oral Prednisone is less likely to cause the liver and kidney problems than the Depo shots, but that otherwise it has the same risk of side effects as Depo shots.
He also told me that oral Prednisone will be fine for her asthma but will not do as good a job controlling her linear granuloma. He added that since linear granuloma is not life threatening, perhaps that does not matter so much to me. However, those little bumps Cheeky gets on the back of her legs bother her, she scratches and bites there a lot. And, I really hate to see those little blackhead-like bumps on her beautiful little nose.
Here are the questions: have any of you had cats who needed long-term steroids? Did any of them develop side effects from either quarterly Depo Medrol shots or long-term use of oral prednisone? If so, what happened?
Any opinions on what I ought to do are welcome. I appreciate your input and thank you in advance.
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Cheryl:
on 02 Feb 2004:
[nq:1]He told me today that oral Prednisone is less likely to cause the liver and kidney problems than the Depo shots, but that otherwise it has the same risk of side effects as Depo shots.[/nq]
Our vet said the exact opposite. Shamrock gets Depo shots for his allergies. Prednisone would be used more consistantly, while depo shots are given "as needed". FTR, Shamrock is so far doing OK with antihistamines. He gets a little spacey sometimes, but one spot actually cleared up on its own without steroids. Another flare-up did require a depo shot, but the vet was surprised about that one spot.

Cheryl
Trapped like rats. In a chia-pet.
MIB II
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Mary:
[nq:1]02 Feb 2004:[/nq]
[nq:2]He told me today that oral Prednisone is less likely ... has the same risk of side effects as Depo shots.[/nq]
[nq:1]Our vet said the exact opposite. Shamrock gets Depo shots for his allergies. Prednisone would be used more consistantly, while ... on its own without steroids. Another flare-up **** a depo shot, but the vet was surprised about that one spot.[/nq]
Cheryl what sort of "spot?" Does Shamrock have linear granuloma too? I know it correlates with allergies. Does Shamrock have asthma, and if not, what are his allergies? Also, please tell me more about these antihistamines, nobody has offered that as an option. Thank you.
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Wendy:
on 02 Feb 2004:
[nq:1]He told me today that oral Prednisone is less likely to cause the liver and kidney problems than the Depo shots, but that otherwise it has the same risk of side effects as Depo shots.[/nq]
Our vet said the exact opposite. Shamrock gets Depo shots for his allergies. Prednisone would be used more consistantly, while depo shots are given "as needed". FTR, Shamrock is so far doing OK with antihistamines. He gets a little spacey sometimes, but one spot actually cleared up on its own without steroids. Another flare-up did require a depo shot, but the vet was surprised about that one spot.

Do you know what Shamrock is allergic to?
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Cheryl:
on 02 Feb 2004:
[nq:1]Cheryl what sort of "spot?" Does Shamrock have linear granuloma too? I know it correlates with allergies. Does Shamrock have asthma, and if not, what are his allergies? Also, please tell me more about these antihistamines, nobody has offered that as an option. Thank you.[/nq]
Shamrock breaks out in lesions and this has been constant since before I even got him he had lesions when I was first asked to foster him. It was suspected that he had flea allergies but when a year went by of keeping him dosed with Advantage like clockwork (even off season), and he'd been examined by different vets MULTIPLE times combing him for fleas or flea dirt, had a skin scrape for mites, cultured for ringworm, and all the while had to have depo shots every 2-3 months (which he always responded to quickly), never a flea was found either on him, in my house or on the other cats. Finally his newest vet diagnosed EGC (eosinophilic granuloma complex) by elimination. I read up on this and found the following article which is why I asked about antihistamines:
http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2002&PID=2544

"Two groups of "alternative" therapies, most of which have been tried in small numbers of cases, only in prospective studies or have been empirically / anecdotally reported as effective, are available.

The first group of "alternative" treatments includes antihistamines and essential fatty acids. These drugs have few reported potential side effects but also few possibilities to work in case of lack of therapeutic efficacy of glucocorticoids. "
Another article stated that sometimes finding the right antihistamine can be trial and error, because while one may have no effect, another might be the right one. I asked the vet about Chlortrimeton (Chlorpheniramine) because of another article I read and she agreed it was worth a shot and gave me the dosage information for him. She said she'd had good results with dogs more than cats with this, but to go ahead and try it. He also is on EFA suppliments (from the vets office, but similar to DermCaps) based on the vin article and a few others who'd stated the same thing.

Cheryl
Trapped like rats. In a chia-pet.
MIB II
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Cheryl:
on 02 Feb 2004:
[nq:1]Do you know what Shamrock is allergic to?[/nq]
No clue. Fleas were ruled out, it could be environmental (household allergies) but he was a stray before I got him and lived outdoors for some time before the caretaker took him to the HS. That certainly doesn't rule out allergens that come into the house from the outdoors but I haven't narrowed it down. I vaccum often and while I don't have a HEPA air cleaner, I have another type that is supposed to elliminate household allergens. It could also be food because I couldn't complete the food trial so I feed him canned food with as few grains as possible (that he will eat!). Tuna seemed to cause a flare-up a while back so I don't give him any food with fish.

Cheryl
Trapped like rats. In a chia-pet.
MIB II
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
-L.:
[nq:1]I need to make a choice about whether to continue Cheeks (4-year-old shelter rescue, female, spayed, and with beautiful intact ... them develop side effects from either quarterly Depo Medrol shots or long-term use of oral prednisone? If so, what happened?[/nq]
My kitty has been on depo medrol off and on for 13 years (eosinophilic granuloma complex) - no effects to date.
-L.
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Mary:
[nq:1]Shamrock breaks out in lesions and this has been constant sincebefore I even got him he had lesions when ... on him, in my house or onthe other cats. Finally his newest vet diagnosed EGC (eosinophilic granuloma complex) by elimination.[/nq]
This is Cheeky's diagnosis it is just the linear kind because she gets it in a straight line on her back legs, I think?

I read up on this and found the following article
[nq:1]which is why I asked about antihistamines:[/nq]
http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2002&PID=2544
[nq:1]"Two groups of "alternative" therapies, most of which have beentried in small numbers of cases, only in prospective studies or have been empirically / anecdotally reported as effective, are available. The first group of "alternative" treatments includes antihistaminesand essential fatty acids.[/nq]
Okay.
[nq:1]These drugs have few reported potential side effects but also few possibilities to work in case of lack of therapeuticefficacy of glucocorticoids. "[/nq]
I don't understand the above sentence. I'll go read the article tomorrow morning when I am fresh. Thanks very much.
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Mary:
[nq:1]My kitty has been on depo medrol off and on for 13 years(eosinophilic granuloma complex) - no effects to date.[/nq]
Ahh, gad, really? That is wonderful news. (I tell you, this skinny little gray tabby has stolen my heart.) Your kitty is not an asthmatic, just the granuloma?
This thread originates from within 'usenet', and as such the content and users are not guaranteed to have been moderated by our community.
Show more