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My dog is a large mixed breed and a rescue when it was thrown out at age 3 wks. We have 3 other dogs (small breeds) and never had an aggression problem. Now the large dogs is over one year old and has always been a sweet obedient, yet a bit skittish dog, who has become very aggressive towards our smallest dog. We had to take her to the vet for treatment. I have them separated now and am getting some professional training, but please can you explain why this has happened? We had her spayed 3 months ago. Could this have contributed to it? I am living in fear with this situation Please help

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